Also known as: Gamma-Linolenic Acid, Evening Primrose Oil
Gamma-linolenic acid (GLA) is an omega-6 fatty acid with anti-inflammatory properties, commonly sourced from evening primrose, borage, and blackcurrant seed oils. Unlike most omega-6 fats, GLA is converted to the anti-inflammatory DGLA.
Gamma-linolenic acid (GLA) is an omega-6 polyunsaturated fatty acid that differs from most omega-6 fats in its anti-inflammatory activity. GLA is metabolized to dihomo-gamma-linolenic acid (DGLA), which produces anti-inflammatory prostaglandin E1. Primary dietary sources include evening primrose oil, borage oil, and blackcurrant seed oil. Clinical research has investigated GLA for conditions including rheumatoid arthritis, diabetic neuropathy, eczema, and PMS. While the body can synthesize GLA from linoleic acid, this conversion is often inefficient due to enzyme limitations, making direct supplementation beneficial for some individuals.
GLA supplementation at 1.400–2.800 mg daily has shown reductions in joint pain, swelling, and morning stiffness in rheumatoid arthritis patients.
GLA supplementation improves skin moisture, elasticity, and reduces symptoms of atopic dermatitis by supporting ceramide production.
With meals
Equivalent to roughly 2–4 g evening primrose oil or 1–2 g borage oil.
Hormonal and skin support
Higher GLA concentration per capsule
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