Also known as: Silica, Orthosilicic Acid, Silicon Dioxide
Silicon is a trace mineral involved in collagen synthesis and connective tissue integrity. Emerging research suggests it supports bone density, skin elasticity, and hair and nail strength, though human evidence is still developing.
Silicon is the third most abundant trace element in the human body and is concentrated in connective tissues including bone, cartilage, skin, hair, and nails. It is believed to play a role in collagen cross-linking and glycosaminoglycan synthesis, contributing to the structural integrity of the extracellular matrix. The Framingham Offspring cohort found that higher dietary silicon intake was positively associated with bone mineral density at the hip in men and premenopausal women. The most bioavailable supplemental form is orthosilicic acid (OSA), which is water-soluble and readily absorbed. While animal studies strongly support silicon's role in bone formation, large-scale randomized human trials remain limited, and no RDA has been established.
Epidemiological data from the Framingham cohort showed a positive association between dietary silicon intake and BMD at the hip. Silicon promotes osteoblast activity and collagen type I synthesis in bone tissue.
A randomized trial found that orthosilicic acid supplementation improved hair tensile strength and thickness, and reduced skin roughness and nail brittleness over 20 weeks.
With a meal
Orthosilicic acid (OSA) provides the most bioavailable form. Effects typically seen after 12–20 weeks.
Highest bioavailability for skin, hair, and bone support
Natural plant-based silicon source
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