Also known as: Thiamin, Thiamine, Aneurin
Vitamin B1 (thiamin) is a water-soluble vitamin essential for carbohydrate metabolism and nervous system function. It acts as a coenzyme in energy-producing pathways and is critical for brain health.
Thiamin, also known as vitamin B1, was the first B vitamin to be identified and plays a pivotal role in energy metabolism. In its active form, thiamin pyrophosphate (TPP), it serves as a coenzyme for pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and transketolase — enzymes central to the citric acid cycle and pentose phosphate pathway. The nervous system is particularly dependent on thiamin due to its high glucose demand. Deficiency leads to beriberi (peripheral neuropathy and cardiovascular dysfunction) and Wernicke-Korsakoff syndrome, most commonly seen in chronic alcohol misuse. Thiamin is not stored in significant amounts and must be replenished daily through diet or supplementation.
Thiamin pyrophosphate is required for the decarboxylation of pyruvate and alpha-ketoglutarate, key steps in aerobic energy production from carbohydrates.
Thiamin is critical for nerve signal transmission and myelin sheath maintenance. Deficiency causes peripheral neuropathy that is reversible with timely supplementation.
With a meal
RDA is 1.2 mg for men and 1.1 mg for women. Higher intake may be needed with high carbohydrate diets.
General supplementation and deficiency prevention
Higher tissue levels and neuropathy support
No product recommendations yet.
No reviews yet. Be the first to share your experience!