Browse our comprehensive directory of evidence-based supplement profiles.
Fatty Acids
Gamma-linolenic acid (GLA) is an omega-6 fatty acid with anti-inflammatory properties, commonly sourced from evening primrose, borage, and blackcurrant seed oils. Unlike most omega-6 fats, GLA is converted to the anti-inflammatory DGLA.
Nootropics
Huperzine A is a naturally occurring alkaloid from Chinese club moss that potently inhibits acetylcholinesterase, increasing acetylcholine levels in the brain. It is studied as both a nootropic and adjunct Alzheimer's therapy.
Specialty & Other
Zeaxanthin is a carotenoid pigment concentrated in the center of the macula, where it provides critical antioxidant protection and blue-light filtering. It is typically supplemented alongside lutein for optimal eye health.
Beta-carotene is the most abundant provitamin A carotenoid in the diet, converted to retinol in the body as needed. It also functions as an antioxidant and plays a role in immune regulation and skin protection against UV damage.
Vitamins
Choline is an essential nutrient required for neurotransmitter synthesis, cell membrane structure, and methyl group metabolism. Despite its importance, most adults do not meet the adequate intake through diet alone.
Herbs
Rose hip is the fruit of Rosa canina, rich in vitamin C, polyphenols, and galactolipids. It is clinically studied for its anti-inflammatory effects in osteoarthritis and its antioxidant properties supporting immune and skin health.
Phosphatidylcholine is the most abundant phospholipid in cell membranes and a major source of choline. It supports liver health, cognitive function, and cell membrane integrity.
Passionflower is a calming herb that modulates GABA-A receptors to reduce anxiety and improve sleep quality. Clinical trials support its efficacy as a natural anxiolytic comparable to low-dose benzodiazepines.
Gymnema sylvestre is a traditional Ayurvedic herb known for its ability to reduce sugar cravings and support healthy blood sugar levels. Its active compounds, gymnemic acids, temporarily block sweet taste receptors and influence glucose metabolism.
Vitamin B5 (pantothenic acid) is a water-soluble vitamin essential for the synthesis of coenzyme A (CoA), a molecule central to fatty acid metabolism, energy production, and the synthesis of hormones and neurotransmitters.
American ginseng is a calming adaptogen native to North America with strong evidence for blood sugar regulation and immune support. Unlike its Asian counterpart, it is considered more cooling and relaxing in traditional use.
Black cohosh (Actaea racemosa) is a North American woodland herb traditionally used to alleviate menopausal symptoms, particularly hot flashes and night sweats. Clinical evidence is moderate, with several trials supporting its efficacy.
Amino Acids
Lysine is an essential amino acid critical for collagen synthesis, calcium absorption, and immune function. It is widely used to prevent and reduce the frequency of herpes simplex outbreaks.
Hops (Humulus lupulus) are the female flower cones of the hop plant, traditionally used in brewing but also valued for their sedative and anxiolytic properties. Clinical studies support their use for sleep improvement, particularly in combination with valerian.
Adaptogens
Shiitake is one of the world's most cultivated and consumed edible mushrooms. Beyond its culinary value, it contains lentinan, a beta-glucan with well-documented immune-modulating and cholesterol-lowering properties.
Nattokinase is a fibrinolytic enzyme extracted from natto, a traditional Japanese fermented soybean food. It has demonstrated the ability to break down fibrin and may support cardiovascular health by promoting healthy blood flow and blood pressure regulation.
Moringa oleifera is a nutrient-dense tropical plant with potent antioxidant and anti-inflammatory properties. Its leaves are exceptionally rich in vitamins, minerals, and bioactive isothiocyanates studied for blood sugar regulation and lipid modulation.
PQQ is a redox-active cofactor that stimulates mitochondrial biogenesis and protects neurons from oxidative damage. It is studied for its potential to enhance cognitive function, energy metabolism, and cellular longevity.
Chlorella is a nutrient-dense freshwater green alga rich in chlorophyll, protein, vitamins, and minerals. It is studied for its potential to support detoxification, immune function, and cholesterol management.
Shilajit is a tar-like resinous substance found in high-altitude mountain rocks, formed over centuries from decomposed plant material. It is rich in fulvic acid and over 80 trace minerals and has been used in Ayurvedic medicine for thousands of years to promote vitality and longevity.