Supplements that strengthen immune defenses.
75 supplements
Minerals
Zinc is an essential trace mineral involved in over 300 enzymatic reactions, playing key roles in immune function, wound healing, and protein synthesis. It is critical for DNA synthesis and cell division.
Vitamins
Vitamin C is a potent water-soluble antioxidant essential for collagen synthesis, immune function, and iron absorption. It cannot be synthesized by humans and must be obtained through diet or supplementation.
Vitamins
Essential fat-soluble vitamin critical for bone health, immune function, and mood regulation. The most common nutrient deficiency worldwide.
Minerals
Iron is an essential trace element required for oxygen transport, energy metabolism, and DNA synthesis. It is a key component of hemoglobin and myoglobin and is one of the most common nutritional deficiencies worldwide.
Vitamins
Vitamin A is a fat-soluble essential nutrient critical for vision, immune function, and cell differentiation. It exists as preformed retinol in animal foods and as provitamin A carotenoids in plant-based sources.
Vitamins
Vitamin B6 is a water-soluble vitamin involved in over 150 enzyme reactions, primarily in amino acid metabolism, neurotransmitter synthesis, and haemoglobin formation. It is essential for brain development and immune function.
Herbs
Turmeric is a golden-yellow spice whose active compound curcumin is one of the most extensively studied natural anti-inflammatory and antioxidant agents. Clinical evidence supports its use for joint health, inflammatory conditions, and general well-being.
Herbs
Ginger is a warming root used for millennia as both a culinary spice and a medicine. Modern research confirms its efficacy against nausea, digestive discomfort, and inflammation, backed by strong clinical evidence.
Herbs
Garlic is one of the oldest medicinal plants, with compelling clinical evidence for cardiovascular benefits including blood pressure reduction and cholesterol modulation. Aged garlic extract is the most studied supplemental form.
Amino Acids
NAC is a stable, bioavailable form of the amino acid cysteine and the most efficient precursor to glutathione, the body's primary intracellular antioxidant. It is widely studied for respiratory, liver, and mental health support.
Probiotics
Lactobacillus rhamnosus GG is one of the most clinically studied probiotic strains worldwide. It is particularly effective in preventing and treating diarrhea and supporting immune resilience in both adults and children.
Probiotics
Lactobacillus acidophilus is one of the most well-studied probiotic strains, naturally found in the human gut and fermented foods. It supports digestive health, immune function, and may help maintain healthy cholesterol levels.
Nootropics
Lion's Mane is an edible medicinal mushroom that stimulates nerve growth factor (NGF) synthesis. It is widely studied for its neuroprotective, cognitive-enhancing, and mood-supporting properties.
Specialty & Other
Spirulina is a cyanobacterium (blue-green algae) cultivated as a nutrient-dense superfood and supplement. It is exceptionally rich in protein, B vitamins, iron, and the unique antioxidant phycocyanin, with clinical evidence supporting benefits for lipid profiles, blood pressure, and blood sugar regulation.
Minerals
Selenium is an essential trace mineral that functions as a component of selenoproteins, which play critical roles in antioxidant defense, thyroid hormone metabolism, and immune function. Adequate selenium status is linked to reduced oxidative stress and cancer risk.
Specialty & Other
Activated charcoal is a highly porous form of carbon used medically for acute poisoning and drug overdose. It adsorbs toxins in the gastrointestinal tract but also indiscriminately binds nutrients and medications, making routine supplementation inadvisable.
Herbs
Elderberry (Sambucus nigra) is a dark purple berry rich in anthocyanins and flavonoids, traditionally used for immune support. Clinical evidence suggests it may reduce the duration and severity of colds and influenza.
Fatty Acids
Cod liver oil is a traditional supplement providing omega-3 EPA/DHA along with naturally occurring vitamins A and D. It has been used for centuries to support bone, immune, and cardiovascular health.
Vitamins
Vitamin E is a group of fat-soluble antioxidants that protect cell membranes from oxidative damage. Alpha-tocopherol is the most biologically active form and the primary form maintained in human plasma.
Herbs
Panax ginseng is an adaptogenic root prized in East Asian medicine for over 2,000 years. Clinical evidence supports its role in reducing fatigue, enhancing cognitive performance, and modulating immune function.
Herbs
Echinacea is a flowering herb widely used to support immune function and reduce the duration and severity of upper respiratory infections. Several species, primarily Echinacea purpurea and Echinacea angustifolia, are used in herbal medicine.
Herbs
Cranberry is a tart berry rich in proanthocyanidins (PACs) that is widely used to support urinary tract health. Research supports its role in preventing recurrent urinary tract infections by inhibiting bacterial adhesion to bladder walls.
Amino Acids
L-Glutamine is the most abundant amino acid in the body, playing essential roles in gut integrity, immune function, and muscle recovery. Demand increases significantly during periods of physical stress, illness, or intense exercise.
Herbs
Black seed (Nigella sativa) is a medicinal plant used for over 2,000 years in traditional medicine. Its primary active compound, thymoquinone, exhibits anti-inflammatory, antioxidant, and immunomodulatory properties with a growing body of clinical evidence.
Herbs
Quercetin is a ubiquitous plant flavonoid with potent antioxidant, anti-inflammatory, and senolytic properties. Clinical research supports its use for allergy relief, cardiovascular protection, and exercise endurance enhancement.
Fatty Acids
Astaxanthin is a powerful carotenoid antioxidant produced by microalgae. It is 6.000 times more potent than vitamin C in singlet oxygen quenching and supports skin, eye, cardiovascular, and exercise recovery.
Specialty & Other
D-Mannose is a simple sugar related to glucose that is used primarily for the prevention and management of urinary tract infections (UTIs). It works by preventing E. coli bacteria from adhering to the walls of the urinary tract, facilitating their excretion in urine.
Herbs
Boswellia serrata resin extract contains boswellic acids, particularly AKBA, which are potent inhibitors of 5-lipoxygenase. It is widely studied for its anti-inflammatory effects in osteoarthritis and inflammatory bowel conditions.
Probiotics
Aloe vera taken internally provides polysaccharides and antioxidant compounds that support gastrointestinal health. It has traditional and some clinical evidence for soothing digestive discomfort, supporting gut lining integrity, and aiding in mild constipation relief.
Probiotics
Sea moss is a red alga rich in minerals, particularly iodine, and contains prebiotic fibers that support gut health. It has a long tradition of use in coastal communities and is gaining popularity as a nutrient-dense whole-food supplement.
Probiotics
Saccharomyces boulardii is a probiotic yeast with strong evidence for preventing and treating multiple forms of diarrhea. Unlike bacterial probiotics, it is naturally resistant to antibiotics, making it ideal for concurrent use during antibiotic therapy.
Adaptogens
Turkey tail is one of the most extensively researched medicinal mushrooms, particularly for immune modulation in cancer care. Its polysaccharide compounds PSK and PSP are approved as adjunctive cancer therapies in Japan and China.
Herbs
Senna is a stimulant laxative herb containing anthraquinone glycosides (sennosides) that act on the large intestine to promote bowel movements. It is clinically validated for short-term treatment of occasional constipation.
Probiotics
Inulin and fructooligosaccharides (FOS) are prebiotic fibers that selectively feed beneficial gut bacteria, particularly Bifidobacterium species. They support digestive regularity, mineral absorption, and a balanced microbiome.
Herbs
Nettle root (Urtica dioica) is traditionally used to support urinary tract health and prostate function. Clinical research suggests it may help manage symptoms of benign prostatic hyperplasia (BPH) and modulate inflammatory pathways.
Herbs
Andrographis paniculata is a bitter herb widely used in Ayurvedic and traditional Chinese medicine for immune support. Its primary bioactive compound, andrographolide, has demonstrated anti-inflammatory, antiviral, and immunomodulatory properties in clinical trials.
Adaptogens
Maitake is a large, edible polypore mushroom native to temperate forests. Its signature compound, D-fraction, is a beta-glucan extract with notable immune-modulating and blood sugar-regulating properties.
Specialty & Other
Propolis is a resinous substance collected by honeybees from tree buds and bark, used to seal and protect the hive. Rich in polyphenols and flavonoids, it has demonstrated antimicrobial, anti-inflammatory, and wound-healing properties in preclinical and preliminary clinical studies.
Specialty & Other
Bromelain is a mixture of proteolytic enzymes derived from the stem and fruit of the pineapple plant (Ananas comosus). It is used for its anti-inflammatory, anti-edema, and fibrinolytic properties, with clinical evidence supporting its use in post-surgical recovery and sinusitis.
Adaptogens
Eleuthero is a woody shrub native to northeastern Asia, widely studied as an adaptogen for stress resistance, physical endurance, and immune modulation. Unlike true ginseng (Panax), it contains eleutherosides rather than ginsenosides as its primary active compounds.
Adaptogens
Cordyceps is a parasitic fungus traditionally used in Tibetan and Chinese medicine to enhance energy, stamina, and respiratory function. Modern research focuses on its benefits for exercise performance and oxygen utilisation.
Herbs
Holy basil (Tulsi) is a revered Ayurvedic adaptogen used for over 3,000 years to combat stress, support immune function, and promote overall well-being. Modern research supports its anxiolytic, anti-inflammatory, and metabolic benefits.
Adaptogens
Reishi is a medicinal mushroom used for over 2.000 years in traditional Chinese medicine. It is valued primarily for its immune-modulating, anti-inflammatory, and calming properties, earning it the title 'mushroom of immortality.'
Herbs
Licorice root (Glycyrrhiza glabra) contains glycyrrhizin and flavonoids with anti-inflammatory, antiviral, and adrenal-supportive properties. It is widely used in traditional medicine but requires caution due to its potential to raise blood pressure through mineralocorticoid activity.
Adaptogens
Astragalus is a foundational herb in Traditional Chinese Medicine, prized for its immune-enhancing, anti-aging, and cardioprotective properties. Modern research has focused on its polysaccharides and cycloastragenol, the latter being studied for its potential to activate telomerase.
Herbs
Olive leaf extract contains oleuropein, a polyphenol with potent antioxidant, antihypertensive, and antimicrobial properties. Clinical evidence supports its use for blood pressure reduction and cardiovascular protection.
Amino Acids
Glutathione is the body's most abundant endogenous antioxidant, a tripeptide composed of glutamate, cysteine, and glycine. It plays a critical role in neutralizing free radicals, detoxifying xenobiotics, and supporting immune function.
Amino Acids
Lysine is an essential amino acid critical for collagen synthesis, calcium absorption, and immune function. It is widely used to prevent and reduce the frequency of herpes simplex outbreaks.
Specialty & Other
Beta-carotene is the most abundant provitamin A carotenoid in the diet, converted to retinol in the body as needed. It also functions as an antioxidant and plays a role in immune regulation and skin protection against UV damage.
Herbs
American ginseng is a calming adaptogen native to North America with strong evidence for blood sugar regulation and immune support. Unlike its Asian counterpart, it is considered more cooling and relaxing in traditional use.
Amino Acids
Methionine is an essential sulfur-containing amino acid that initiates protein synthesis and serves as the precursor to SAMe, cysteine, and taurine. It plays key roles in methylation, detoxification, and antioxidant defense.
Herbs
Moringa oleifera is a nutrient-dense tropical plant with potent antioxidant and anti-inflammatory properties. Its leaves are exceptionally rich in vitamins, minerals, and bioactive isothiocyanates studied for blood sugar regulation and lipid modulation.
Fatty Acids
Gamma-linolenic acid (GLA) is an omega-6 fatty acid with anti-inflammatory properties, commonly sourced from evening primrose, borage, and blackcurrant seed oils. Unlike most omega-6 fats, GLA is converted to the anti-inflammatory DGLA.
Herbs
Rose hip is the fruit of Rosa canina, rich in vitamin C, polyphenols, and galactolipids. It is clinically studied for its anti-inflammatory effects in osteoarthritis and its antioxidant properties supporting immune and skin health.
Probiotics
Bifidobacterium longum is a foundational member of the human gut microbiome from birth. It supports digestive comfort, immune balance, and emerging research links it to stress and mood regulation via the gut-brain axis.
Adaptogens
Shiitake is one of the world's most cultivated and consumed edible mushrooms. Beyond its culinary value, it contains lentinan, a beta-glucan with well-documented immune-modulating and cholesterol-lowering properties.
Specialty & Other
Chlorella is a nutrient-dense freshwater green alga rich in chlorophyll, protein, vitamins, and minerals. It is studied for its potential to support detoxification, immune function, and cholesterol management.
Herbs
Evening primrose oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid with anti-inflammatory properties. It is commonly used for skin health, PMS symptoms, and eczema management.
Adaptogens
Chaga is a slow-growing parasitic fungus found primarily on birch trees in cold climates. It has been used for centuries in Siberian and Northern European folk medicine for its potent antioxidant and immune-supporting properties.
Herbs
Oregano oil is rich in carvacrol and thymol, phenolic compounds with potent antimicrobial, antifungal, and antioxidant properties. It is primarily used for immune support and upper respiratory tract infections.
Herbs
Dandelion is a traditional medicinal herb used for centuries as a diuretic and digestive aid. Modern research supports its hepatoprotective properties and mild diuretic effect without significant potassium loss.
Specialty & Other
Bee pollen is a nutrient-dense mixture of flower pollen, nectar, and bee secretions collected by honeybees. It contains proteins, vitamins, and antioxidants, with preliminary evidence suggesting anti-inflammatory and immune-modulating properties, though large-scale clinical trials are lacking.
Specialty & Other
Serrapeptase is a proteolytic enzyme originally isolated from the bacterium Serratia marcescens in the intestine of the silkworm. It is used as an anti-inflammatory and mucolytic agent, with preliminary evidence supporting its role in reducing swelling and pain after surgical procedures.
Specialty & Other
Kelp is a large brown seaweed rich in iodine, fucoidan, and other bioactive compounds. It is primarily used as a natural iodine source for thyroid support, though excessive intake carries a significant risk of iodine-induced thyroid dysfunction.
Specialty & Other
Diindolylmethane (DIM) is a compound formed from the digestion of indole-3-carbinol, found in cruciferous vegetables. It modulates estrogen metabolism by promoting the formation of favorable 2-hydroxyestrone metabolites and is studied for its potential role in hormone-dependent cancer prevention.
Specialty & Other
Wheatgrass is the young grass of the common wheat plant, rich in chlorophyll, vitamins, minerals, and antioxidants. It is traditionally consumed as juice or powder for general wellness and antioxidant support.
Herbs
Slippery elm is a demulcent herb derived from the inner bark of Ulmus rubra, rich in mucilage polysaccharides. It forms a protective gel over mucosal surfaces and is traditionally used for soothing the gastrointestinal tract and throat irritation.
Specialty & Other
Indole-3-Carbinol (I3C) is a naturally occurring compound found in cruciferous vegetables that modulates estrogen metabolism and has shown chemopreventive properties. It is a precursor to DIM and other bioactive condensation products formed during digestion.
Herbs
Cat's Claw is a tropical vine native to the Amazon rainforest, traditionally used for its anti-inflammatory and immune-modulating properties. It contains oxindole alkaloids that may support immune function and reduce inflammation.
Herbs
Goldenseal is a North American woodland plant valued for its antimicrobial alkaloid berberine. It has traditionally been used for respiratory infections, digestive issues, and mucosal inflammation.
Fatty Acids
Omega-7 (palmitoleic acid) is a monounsaturated fatty acid found in sea buckthorn and macadamia nuts. It supports mucosal membrane health, cardiovascular function, and metabolic markers.
Herbs
Noni (Morinda citrifolia) is a tropical fruit used in Polynesian traditional medicine for immune support and general vitality. It contains iridoids, flavonoids, and polysaccharides with antioxidant and immunomodulatory properties, though high-quality clinical evidence remains limited.
Specialty & Other
Colloidal silver is a suspension of silver particles in liquid marketed as an alternative health product. The FDA has stated that colloidal silver is not generally recognized as safe or effective for treating any disease or condition, and its use can cause permanent side effects including argyria.
Specialty & Other
Pau d'Arco is the inner bark of several Tabebuia tree species native to South America, traditionally used for infections and inflammation. Its key compound, beta-lapachone, shows antimicrobial and anti-inflammatory activity in vitro, but human clinical evidence is very limited.
Specialty & Other
Thunder God Vine is a traditional Chinese medicinal plant with potent immunosuppressive and anti-inflammatory properties. While some clinical trials suggest efficacy for rheumatoid arthritis, it carries serious toxicity risks affecting the liver, kidneys, reproductive system, and bone marrow.